Cancer Study Shows Benefits of Resection for Advanced-Stage Melanoma


Melanoma pic

Heywood Medical Group physician and staff surgeon Dr. Konstantino Avradopoulos has handled more than 4,500 medical cases and complex surgeries while working at teaching hospitals over the last decade. In addition to his hospital work, Dr. Konstantino Avradopoulos has participated in numerous medical studies. His work was cited in a 2004 paper on contemporary surgical treatments for patients with advanced-stage melanoma.

The 29-year study involved using clinicopathologic factors to estimate the survival rate of patients with Stage IV melanoma following corrective surgeries. The five-year survival rate for such patients is about 5 percent, making surgical treatment a controversial choice, according to the criteria of the American Joint Committee on Cancer (AJCC).

Researchers in the study analyzed 1,574 patients at the Tertiary Cancer Center who received surgical resections for metastatic melanoma. Surgical resection techniques varied, based on where the cancer metastasized, and researchers used a computer-assisted database to conduct statistical analysis.

At the end of the study, researchers concluded that surgical resection benefited the majority of patients with advanced-stage melanoma. The number of metastases and the sites affected played a significant role in the improvement of five-year survival rates, Patients with skin and lymph node metastases showed the most favorable results. These patients accounted for 19 percent of those examined. Additionally, the study indicated that patients with limited metastases and site areas benefit from curative resection, regardless of the disease’s location.